Nepal has faced multiple severe natural calamities, such as the devastating earthquakes of 2015 in Kathmandu on 23 April which killed more 9000 people and destroyed around 7,00,000 homes and earthquake on 4 Nov 2023 in Jajarkot of Karnali Pradesh leaving behind around 1 lakh people homeless, and the global COVID-19 pandemic. During these crises, Patanjali Yogpeeth Nepal has emerged as a selfless lifeline for the people with all the volunteers providing their assistance as per need and capacity. From providing emergency relief supplies like food, clothes, temporary shelter and tarpaulin, medical aid, and rehabilitation efforts post-earthquake to supporting the health and well-being of citizens during the natural calamities and pandemic, Patanjali's involvement has been invaluable. Under the leadership of Yog Rishi His Holiness Swami Ji Maharaj and Ayurved Shiromani His Holiness Acharya Ji Maharaj, their initiatives have shown deep commitment to serving communities in their times of need.

some of the services provide during 2015 Earthquake were:

• First Organization to come in front in helping and rehabilitating the people.
• Organized Blood Donation Camp
• Distributed medicines worth more than Rs 1 Crore
• Contribution of more than Rs 5 Crore in relief work
• Installed 30 Relief camps
• Selfless service by 30,000 volunteers

Similarly, some of the relief work done during 2023 earthquake of Jajarkot include:

• Kitchen installed at 5 places for thousands of people in need.
• Contribution of around Rs 2 crore as relief work
• Selfless service by hundreds of volunteers.